Fibronectin type III domain-containing protein 1 (FNDC1)
Homo sapiens — UniProt Q4ZHG4
Data last refreshed: (UniProt release unknown)
Key facts
Fibronectin type III domain-containing protein 1 (FNDC1) is a protein from Homo sapiens identified by UniProt accession Q4ZHG4, 1894 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q4ZHG4; gene symbol FNDC1.
- Organism: Homo sapiens.
- Length: 1894 amino acids.
- Top disease associations (Open Targets): pulse pressure measurement, systolic blood pressure and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fibronectin type III domain-containing protein 1 |
|---|---|
| UniProt accession | Q4ZHG4 |
| Gene | FNDC1 |
| Organism | Homo sapiens |
| Length | 1894 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.46
- systolic blood pressure · score 0.38
- urate measurement · score 0.31
- bone density · score 0.31
- lipoprotein A measurement · score 0.31
- joint hypermobility measurement · score 0.30
- eosinophil count · score 0.18
- leukocyte count · score 0.17
- electrocardiography · score 0.12
- QRS duration · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4ZHG4-F1 | alphafold | PREDICTED | 53.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4ZHG4.
Amino-acid sequence (1894 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNDC1?
The strongest Open Targets associations for FNDC1 are pulse pressure measurement, systolic blood pressure, urate measurement, bone density and lipoprotein A measurement.
How long is the FNDC1 protein?
The Homo sapiens FNDC1 protein (UniProt Q4ZHG4) is 1894 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4ZHG4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4ZHG4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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