Sodium/hydrogen exchanger 9B1 (SLC9B1)
Homo sapiens — UniProt Q4ZJI4
Data last refreshed: (UniProt release unknown)
Key facts
Sodium/hydrogen exchanger 9B1 (SLC9B1) is a protein from Homo sapiens identified by UniProt accession Q4ZJI4, 515 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q4ZJI4; gene symbol SLC9B1.
- Organism: Homo sapiens.
- Length: 515 amino acids.
- Top disease associations (Open Targets): Wolfram syndrome, alkaline phosphatase measurement and Usher syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium/hydrogen exchanger 9B1 |
|---|---|
| UniProt accession | Q4ZJI4 |
| Gene | SLC9B1 |
| Organism | Homo sapiens |
| Length | 515 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- Wolfram syndrome · score 0.36
- alkaline phosphatase measurement · score 0.34
- Usher syndrome · score 0.34
- glomerular filtration rate · score 0.34
- schizophrenia · score 0.31
- atrial fibrillation · score 0.31
- type 2 diabetes mellitus · score 0.30
- serum urea measurement · score 0.25
- sex hormone-binding globulin measurement · score 0.25
- diastolic blood pressure · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4ZJI4-F1 | alphafold | PREDICTED | 79.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4ZJI4.
Amino-acid sequence (515 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC9B1?
The strongest Open Targets associations for SLC9B1 are Wolfram syndrome, alkaline phosphatase measurement, Usher syndrome, glomerular filtration rate and schizophrenia.
How long is the SLC9B1 protein?
The Homo sapiens SLC9B1 protein (UniProt Q4ZJI4) is 515 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4ZJI4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4ZJI4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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