Ankyrin repeat domain-containing protein SOWAHC (SOWAHC)
Homo sapiens — UniProt Q53LP3
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein SOWAHC (SOWAHC) is a protein from Homo sapiens identified by UniProt accession Q53LP3, 525 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q53LP3; gene symbol SOWAHC.
- Organism: Homo sapiens.
- Length: 525 amino acids.
- Top disease associations (Open Targets): platelet count, platelet crit and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein SOWAHC |
|---|---|
| UniProt accession | Q53LP3 |
| Gene | SOWAHC |
| Organism | Homo sapiens |
| Length | 525 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- platelet count · score 0.35
- platelet crit · score 0.30
- neurodegenerative disease · score 0.27
- schizophrenia · score 0.17
- bone density · score 0.08
- urate measurement · score 0.08
- physical activity · score 0.06
- body fat percentage · score 0.06
- traffic air pollution measurement · score 0.03
- cortical surface area measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q53LP3-F1 | alphafold | PREDICTED | 60.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q53LP3.
Amino-acid sequence (525 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOWAHC?
The strongest Open Targets associations for SOWAHC are platelet count, platelet crit, neurodegenerative disease, schizophrenia and bone density.
How long is the SOWAHC protein?
The Homo sapiens SOWAHC protein (UniProt Q53LP3) is 525 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q53LP3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q53LP3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.