Outer dense fiber protein 2 (ODF2)
Homo sapiens — UniProt Q5BJF6
Data last refreshed: (UniProt release unknown)
Key facts
Outer dense fiber protein 2 (ODF2) is a protein from Homo sapiens identified by UniProt accession Q5BJF6, 829 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q5BJF6; gene symbol ODF2.
- Organism: Homo sapiens.
- Length: 829 amino acids.
- Top disease associations (Open Targets): ovarian cancer, breast adenocarcinoma and pancreatic adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Outer dense fiber protein 2 |
|---|---|
| UniProt accession | Q5BJF6 |
| Gene | ODF2 |
| Organism | Homo sapiens |
| Length | 829 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.23
- breast adenocarcinoma · score 0.23
- pancreatic adenocarcinoma · score 0.12
- azoospermia · score 0.11
- pulse pressure measurement · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.09
- spermatogenic failure 43 · score 0.09
- spermatogenic failure 49 · score 0.09
- spermatogenic failure 45 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5BJF6-F1 | alphafold | PREDICTED | 78.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5BJF6.
Amino-acid sequence (829 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ODF2?
The strongest Open Targets associations for ODF2 are ovarian cancer, breast adenocarcinoma, pancreatic adenocarcinoma, azoospermia and pulse pressure measurement.
How long is the ODF2 protein?
The Homo sapiens ODF2 protein (UniProt Q5BJF6) is 829 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5BJF6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5BJF6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.