Protein YIF1B (YIF1B)

About Protein YIF1B

Protein YIF1B (YIF1B) is a protein from Homo sapiens identified by UniProt accession Q5BJH7, 314 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Protein YIF1B
UniProt accession	Q5BJH7
Gene	YIF1B
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

Kaya-Barakat-Masson syndrome · score 0.63
Global developmental delay · score 0.49
Abnormality of movement · score 0.49
Seizure · score 0.49
Hypotonia · score 0.49
Spasticity · score 0.49
Intellectual disability · score 0.49
Failure to thrive · score 0.49
Microcephaly · score 0.49
microcephaly · score 0.49

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5BJH7-F1	alphafold	PREDICTED	73.27	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5BJH7.

Amino-acid sequence (314 residues)

MHPAGLAAAA AGTPRLRKWP SKRRIPVSQP GMADPHQLFD DTSSAQSRGY GAQRAPGGLS YPAASPTPHA AFLADPVSNM AMAYGSSLAA QGKELVDKNI DRFIPITKLK YYFAVDTMYV GRKLGLLFFP YLHQDWEVQY QQDTPVAPRF DVNAPDLYIP AMAFITYVLV AGLALGTQDR FSPDLLGLQA SSALAWLTLE VLAILLSLYL VTVNTDLTTI DLVAFLGYKY VGMIGGVLMG LLFGKIGYYL VLGWCCVAIF VFMIRTLRLK ILADAAAEGV PVRGARNQLR MYLTMAVAAA QPMLMYWLTF HLVR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards