Leucine-rich repeat-containing protein 10 (LRRC10)
Homo sapiens — UniProt Q5BKY1
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 10 (LRRC10) is a protein from Homo sapiens identified by UniProt accession Q5BKY1, 277 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.
- UniProt accession: Q5BKY1; gene symbol LRRC10.
- Organism: Homo sapiens.
- Length: 277 amino acids.
- Top disease associations (Open Targets): atrial fibrillation, autosomal dominant dilated cardiomyopathy and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 10 |
|---|---|
| UniProt accession | Q5BKY1 |
| Gene | LRRC10 |
| Organism | Homo sapiens |
| Length | 277 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (139)
Diseases linked to this target (Open Targets).
- atrial fibrillation · score 0.22
- autosomal dominant dilated cardiomyopathy · score 0.19
- systolic blood pressure · score 0.15
- Dilated cardiomyopathy · score 0.09
- hypertrophic cardiomyopathy · score 0.08
- dilated cardiomyopathy · score 0.07
- left ventricular noncompaction · score 0.07
- dilated cardiomyopathy 1W · score 0.06
- dilated cardiomyopathy 1CC · score 0.06
- dilated cardiomyopathy 1JJ · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5BKY1-F1 | alphafold | PREDICTED | 86.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5BKY1.
Amino-acid sequence (277 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC10?
The strongest Open Targets associations for LRRC10 are atrial fibrillation, autosomal dominant dilated cardiomyopathy, systolic blood pressure, Dilated cardiomyopathy and hypertrophic cardiomyopathy.
How long is the LRRC10 protein?
The Homo sapiens LRRC10 protein (UniProt Q5BKY1) is 277 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5BKY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5BKY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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