Protein FAM133B (FAM133B)
Homo sapiens — UniProt Q5BKY9
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM133B (FAM133B) is a protein from Homo sapiens identified by UniProt accession Q5BKY9, 247 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q5BKY9; gene symbol FAM133B.
- Organism: Homo sapiens.
- Length: 247 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cardiovascular disease and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM133B |
|---|---|
| UniProt accession | Q5BKY9 |
| Gene | FAM133B |
| Organism | Homo sapiens |
| Length | 247 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- cardiovascular disease · score 0.24
- heel bone mineral density · score 0.18
- lean body mass · score 0.15
- mean corpuscular volume · score 0.15
- mean corpuscular hemoglobin concentration · score 0.15
- bone quantitative ultrasound measurement · score 0.15
- body height · score 0.15
- pulse pressure measurement · score 0.14
- monocyte percentage of leukocytes · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5BKY9-F1 | alphafold | PREDICTED | 62.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5BKY9.
Amino-acid sequence (247 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM133B?
The strongest Open Targets associations for FAM133B are neurodegenerative disease, cardiovascular disease, heel bone mineral density, lean body mass and mean corpuscular volume.
How long is the FAM133B protein?
The Homo sapiens FAM133B protein (UniProt Q5BKY9) is 247 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5BKY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5BKY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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