TPA-induced transmembrane protein (TTMP)
Homo sapiens — UniProt Q5BVD1
Data last refreshed: (UniProt release unknown)
Key facts
TPA-induced transmembrane protein (TTMP) is a protein from Homo sapiens identified by UniProt accession Q5BVD1, 217 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q5BVD1; gene symbol TTMP.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): eosinophil count, eosinophil percentage of leukocytes and eosinophil percentage of granulocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TPA-induced transmembrane protein |
|---|---|
| UniProt accession | Q5BVD1 |
| Gene | TTMP |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.23
- eosinophil percentage of leukocytes · score 0.17
- eosinophil percentage of granulocytes · score 0.09
- sum of eosinophil and basophil counts · score 0.09
- neutrophil percentage of granulocytes · score 0.07
- glucuronate measurement · score 0.07
- neoplasm · score 0.01
- oral squamous cell carcinoma · score 0.01
- chronic interstitial cystitis · score 0.01
- hypotrichosis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5BVD1-F1 | alphafold | PREDICTED | 75.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5BVD1.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTMP?
The strongest Open Targets associations for TTMP are eosinophil count, eosinophil percentage of leukocytes, eosinophil percentage of granulocytes, sum of eosinophil and basophil counts and neutrophil percentage of granulocytes.
How long is the TTMP protein?
The Homo sapiens TTMP protein (UniProt Q5BVD1) is 217 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5BVD1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5BVD1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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