Nucleolar MIF4G domain-containing protein 1 (NOM1)
Homo sapiens — UniProt Q5C9Z4
Data last refreshed: (UniProt release unknown)
Key facts
Nucleolar MIF4G domain-containing protein 1 (NOM1) is a protein from Homo sapiens identified by UniProt accession Q5C9Z4, 860 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q5C9Z4; gene symbol NOM1.
- Organism: Homo sapiens.
- Length: 860 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, MODY and IGF-1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleolar MIF4G domain-containing protein 1 |
|---|---|
| UniProt accession | Q5C9Z4 |
| Gene | NOM1 |
| Organism | Homo sapiens |
| Length | 860 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- MODY · score 0.07
- IGF-1 measurement · score 0.06
- 3-hydroxy-3-methylglutaryl-CoA synthase deficiency · score 0.05
- hyperproinsulinemia · score 0.05
- exercise-induced hyperinsulinism · score 0.04
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- pulse wave reflection index measurement · score 0.04
- hyperinsulinism due to INSR deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5C9Z4-F1 | alphafold | PREDICTED | 69.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5C9Z4.
Amino-acid sequence (860 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOM1?
The strongest Open Targets associations for NOM1 are neurodegenerative disease, MODY, IGF-1 measurement, 3-hydroxy-3-methylglutaryl-CoA synthase deficiency and hyperproinsulinemia.
How long is the NOM1 protein?
The Homo sapiens NOM1 protein (UniProt Q5C9Z4) is 860 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5C9Z4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5C9Z4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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