About DALR anticodon-binding domain-containing protein 3
DALR anticodon-binding domain-containing protein 3 (DALRD3) is a protein
from Homo sapiens identified by UniProt accession
Q5D0E6, 543 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (42)
Diseases linked to this target (Open Targets).
- mitochondrial complex I deficiency · score 0.46
- developmental and epileptic encephalopathy, 86 · score 0.41
- neurodegenerative disease · score 0.40
- undetermined early-onset epileptic encephalopathy · score 0.37
- genetic disorder · score 0.17
- mean corpuscular volume · score 0.13
- bilirubin measurement · score 0.10
- BMI-adjusted waist-hip ratio · score 0.09
- HbA1c measurement · score 0.07
- major depressive disorder · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q5D0E6.
Amino-acid sequence (543 residues)
MATRRLGVGE TLGALNAALG PGGPVWIKET RTRHLRSRDF LAPHRALQAR FDDGQVPEHL LHALACLQGP GVAPVLRCAP TPAGLSLQLQ RSAVFERVLS AVAAYATPAS PASLGQRVLL HCPALRSSPC ALRLSQLRTV LVADHLARAL RAHGVCVRLV PAVRDPHMLT FLQQLRVDWP AASERASSHT LRSHALEELT SANDGRTLSP GILGRLCLKE LVEEQGRTAG YDPNLDNCLV TEDLLSVLAE LQEALWHWPE DSHPGLAGAS DTGTGGCLVV HVVSCEEEFQ QQKLDLLWQK LVDKAPLRQK HLICGPVKVA GAPGTLMTAP EYYEFRHTQV CKASALKHGG DLAQDPAWTE IFGVLSVATI KFEMLSTAPQ SQLFLALADS SISTKGTKSG TFVMYNCARL ATLFESYKCS MEQGLYPTFP PVSSLDFSLL HDEGEWLLLF NSILPFPDLL SRTAVLDCTA PGLHIAVRTE MICKFLVQLS MDFSSYYNRV HILGEPRPHL FGQMFVRLQL LRAVREVLHT GLAMLGLPPL SHI
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