Endoribonuclease ZC3H12A (ZC3H12A)
Homo sapiens — UniProt Q5D1E8
Data last refreshed: (UniProt release unknown)
Key facts
Endoribonuclease ZC3H12A (ZC3H12A) is a protein from Homo sapiens identified by UniProt accession Q5D1E8, 599 residues long. MolForge cross-references it against 0 known binders and 439 disease associations.
- UniProt accession: Q5D1E8; gene symbol ZC3H12A.
- Organism: Homo sapiens.
- Length: 599 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, monocyte count and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endoribonuclease ZC3H12A |
|---|---|
| UniProt accession | Q5D1E8 |
| Gene | ZC3H12A |
| Organism | Homo sapiens |
| Length | 599 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (439)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.28
- monocyte count · score 0.28
- Red cell distribution width · score 0.26
- mean corpuscular hemoglobin · score 0.25
- mean corpuscular hemoglobin concentration · score 0.24
- neurodegenerative disease · score 0.24
- red blood cell density measurement · score 0.23
- cognitive function measurement · score 0.20
- C-reactive protein measurement · score 0.19
- mathematical ability · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5D1E8-F1 | alphafold | PREDICTED | 66.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5D1E8.
Amino-acid sequence (599 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZC3H12A?
The strongest Open Targets associations for ZC3H12A are mean corpuscular volume, monocyte count, Red cell distribution width, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
How long is the ZC3H12A protein?
The Homo sapiens ZC3H12A protein (UniProt Q5D1E8) is 599 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5D1E8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5D1E8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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