PDZ domain-containing protein 11 (PDZD11)
Homo sapiens — UniProt Q5EBL8
Data last refreshed: (UniProt release unknown)
Key facts
PDZ domain-containing protein 11 (PDZD11) is a protein from Homo sapiens identified by UniProt accession Q5EBL8, 140 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q5EBL8; gene symbol PDZD11.
- Organism: Homo sapiens.
- Length: 140 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, endometrial cancer and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PDZ domain-containing protein 11 |
|---|---|
| UniProt accession | Q5EBL8 |
| Gene | PDZD11 |
| Organism | Homo sapiens |
| Length | 140 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- endometrial cancer · score 0.15
- squamous cell lung carcinoma · score 0.14
- head and neck squamous cell carcinoma · score 0.12
- cutaneous melanoma · score 0.12
- cancer · score 0.03
- neoplasm · score 0.03
- ulcerative colitis · score 0.01
- cyst · score 0.01
- Meningitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5EBL8-F1 | alphafold | PREDICTED | 82.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5EBL8.
Amino-acid sequence (140 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDZD11?
The strongest Open Targets associations for PDZD11 are neurodegenerative disease, endometrial cancer, squamous cell lung carcinoma, head and neck squamous cell carcinoma and cutaneous melanoma.
How long is the PDZD11 protein?
The Homo sapiens PDZD11 protein (UniProt Q5EBL8) is 140 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5EBL8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5EBL8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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