UMP-CMP kinase 2, mitochondrial (CMPK2)
Homo sapiens — UniProt Q5EBM0
Data last refreshed: (UniProt release unknown)
Key facts
UMP-CMP kinase 2, mitochondrial (CMPK2) is a protein from Homo sapiens identified by UniProt accession Q5EBM0, 449 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q5EBM0; gene symbol CMPK2.
- Organism: Homo sapiens.
- Length: 449 amino acids.
- Top disease associations (Open Targets): risk-taking behaviour, neurofibrillary tangles measurement and balding measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UMP-CMP kinase 2, mitochondrial |
|---|---|
| UniProt accession | Q5EBM0 |
| Gene | CMPK2 |
| Organism | Homo sapiens |
| Length | 449 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- risk-taking behaviour · score 0.28
- neurofibrillary tangles measurement · score 0.27
- balding measurement · score 0.26
- hair shape measurement · score 0.25
- visual perception measurement · score 0.23
- alopecia · score 0.20
- androgenetic alopecia · score 0.19
- metastasis measurement · score 0.18
- disease progression measurement · score 0.18
- breast milk measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5EBM0-F1 | alphafold | PREDICTED | 86.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5EBM0.
Amino-acid sequence (449 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CMPK2?
The strongest Open Targets associations for CMPK2 are risk-taking behaviour, neurofibrillary tangles measurement, balding measurement, hair shape measurement and visual perception measurement.
How long is the CMPK2 protein?
The Homo sapiens CMPK2 protein (UniProt Q5EBM0) is 449 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5EBM0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5EBM0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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