Putative tripartite motif-containing protein 61 (TRIM61)
Homo sapiens — UniProt Q5EBN2
Data last refreshed: (UniProt release unknown)
Key facts
Putative tripartite motif-containing protein 61 (TRIM61) is a protein from Homo sapiens identified by UniProt accession Q5EBN2, 209 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q5EBN2; gene symbol TRIM61.
- Organism: Homo sapiens.
- Length: 209 amino acids.
- Top disease associations (Open Targets): ovarian carcinoma, DNA methylation and Ischemic stroke.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative tripartite motif-containing protein 61 |
|---|---|
| UniProt accession | Q5EBN2 |
| Gene | TRIM61 |
| Organism | Homo sapiens |
| Length | 209 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.29
- DNA methylation · score 0.21
- Ischemic stroke · score 0.04
- cancer · score 0.00
- breast cancer · score 0.00
- squamous cell lung carcinoma · score 0.00
- Klinefelter's syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5EBN2-F1 | alphafold | PREDICTED | 85.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5EBN2.
Amino-acid sequence (209 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIM61?
The strongest Open Targets associations for TRIM61 are ovarian carcinoma, DNA methylation, Ischemic stroke, cancer and breast cancer.
How long is the TRIM61 protein?
The Homo sapiens TRIM61 protein (UniProt Q5EBN2) is 209 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5EBN2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5EBN2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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