Arylsulfatase J (ARSJ)
Homo sapiens — UniProt Q5FYB0
Data last refreshed: (UniProt release unknown)
Key facts
Arylsulfatase J (ARSJ) is a protein from Homo sapiens identified by UniProt accession Q5FYB0, 599 residues long. MolForge cross-references it against 0 known binders and 93 disease associations.
- UniProt accession: Q5FYB0; gene symbol ARSJ.
- Organism: Homo sapiens.
- Length: 599 amino acids.
- Top disease associations (Open Targets): body height, intraocular pressure measurement and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arylsulfatase J |
|---|---|
| UniProt accession | Q5FYB0 |
| Gene | ARSJ |
| Organism | Homo sapiens |
| Length | 599 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (93)
Diseases linked to this target (Open Targets).
- body height · score 0.47
- intraocular pressure measurement · score 0.33
- lean body mass · score 0.32
- body mass index · score 0.27
- body weight · score 0.25
- appendicular lean mass · score 0.23
- adolescent idiopathic scoliosis · score 0.18
- glycerophospholipid measurement · score 0.10
- fat body mass · score 0.09
- base metabolic rate measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5FYB0-F1 | alphafold | PREDICTED | 86.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5FYB0.
Amino-acid sequence (599 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARSJ?
The strongest Open Targets associations for ARSJ are body height, intraocular pressure measurement, lean body mass, body mass index and body weight.
How long is the ARSJ protein?
The Homo sapiens ARSJ protein (UniProt Q5FYB0) is 599 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5FYB0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5FYB0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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