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XK-related protein 9 (XKR9)

Homo sapiens — UniProt Q5GH70

Gene: XKR9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

XK-related protein 9 (XKR9) is a protein from Homo sapiens identified by UniProt accession Q5GH70, 373 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q5GH70; gene symbol XKR9.
  • Organism: Homo sapiens.
  • Length: 373 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, neurodegenerative disease and hemorrhoid.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameXK-related protein 9
UniProt accessionQ5GH70
GeneXKR9
OrganismHomo sapiens
Length373 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.44
  • neurodegenerative disease · score 0.37
  • hemorrhoid · score 0.34
  • cortical surface area measurement · score 0.33
  • BMI-adjusted waist-hip ratio · score 0.31
  • triglyceride measurement · score 0.31
  • FEV/FVC ratio · score 0.27
  • BMI-adjusted waist circumference · score 0.27
  • snoring measurement · score 0.27
  • erythrocyte cadmium measurement · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5GH70-F1alphafoldPREDICTED84.76—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5GH70.

Amino-acid sequence (373 residues)

MKYTKQNFMM SVLGIIIYVT DLIVDIWVSV RFFHEGQYVF SALALSFMLF GTLVAQCFSY SWFKADLKKA GQESQHCFLL LHCLQGGVFT RYWFALKRGY HAAFKYDSNT SNFVEEQIDL HKEVIDRVTD LSMLRLFETY LEGCPQLILQ LYILLEHGQA NFSQYAAIMV SCCAISWSTV DYQVALRKSL PDKKLLNGLC PKITYLFYKL FTLLSWMLSV VLLLFLNVKI ALFLLLFLWL LGIIWAFKNN TQFCTCISME FLYRIVVGFI LIFTFFNIKG QNTKCPMSCY YIVRVLGTLG ILTVFWVCPL TIFNPDYFIP ISITIVLTLL LGILFLIVYY GSFHPNRSAE TKCDEIDGKP VLRECRMRYF LME

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with XKR9?

The strongest Open Targets associations for XKR9 are heel bone mineral density, neurodegenerative disease, hemorrhoid, cortical surface area measurement and BMI-adjusted waist-hip ratio.

How long is the XKR9 protein?

The Homo sapiens XKR9 protein (UniProt Q5GH70) is 373 amino acids long.

Browse: Targets: X · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5GH70
GeneXKR9
OrganismHomo sapiens
Length373
Binders0
Diseases44
View on UniProt