Neuromedin-S (NMS)
Homo sapiens — UniProt Q5H8A3
Data last refreshed: (UniProt release unknown)
Key facts
Neuromedin-S (NMS) is a protein from Homo sapiens identified by UniProt accession Q5H8A3, 153 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q5H8A3; gene symbol NMS.
- Organism: Homo sapiens.
- Length: 153 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, ovarian cancer and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuromedin-S |
|---|---|
| UniProt accession | Q5H8A3 |
| Gene | NMS |
| Organism | Homo sapiens |
| Length | 153 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.27
- ovarian cancer · score 0.26
- breast adenocarcinoma · score 0.25
- mathematical ability · score 0.21
- head and neck squamous cell carcinoma · score 0.16
- self reported educational attainment · score 0.12
- prostate adenocarcinoma · score 0.10
- protein measurement · score 0.03
- infection · score 0.02
- infect · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H8A3-F1 | alphafold | PREDICTED | 62.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H8A3.
Amino-acid sequence (153 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NMS?
The strongest Open Targets associations for NMS are glioblastoma multiforme, ovarian cancer, breast adenocarcinoma, mathematical ability and head and neck squamous cell carcinoma.
How long is the NMS protein?
The Homo sapiens NMS protein (UniProt Q5H8A3) is 153 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H8A3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H8A3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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