Solute carrier family 25 member 53 (SLC25A53)
Homo sapiens — UniProt Q5H9E4
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 25 member 53 (SLC25A53) is a protein from Homo sapiens identified by UniProt accession Q5H9E4, 307 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q5H9E4; gene symbol SLC25A53.
- Organism: Homo sapiens.
- Length: 307 amino acids.
- Top disease associations (Open Targets): 15q11q13 microduplication syndrome, myocardial infarction and Sjogren syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 25 member 53 |
|---|---|
| UniProt accession | Q5H9E4 |
| Gene | SLC25A53 |
| Organism | Homo sapiens |
| Length | 307 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- 15q11q13 microduplication syndrome · score 0.12
- myocardial infarction · score 0.01
- Sjogren syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9E4-F1 | alphafold | PREDICTED | 85.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9E4.
Amino-acid sequence (307 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC25A53?
The strongest Open Targets associations for SLC25A53 are 15q11q13 microduplication syndrome, myocardial infarction and Sjogren syndrome.
How long is the SLC25A53 protein?
The Homo sapiens SLC25A53 protein (UniProt Q5H9E4) is 307 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9E4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9E4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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