BCL-6 corepressor-like protein 1 (BCORL1)
Homo sapiens — UniProt Q5H9F3
Data last refreshed: (UniProt release unknown)
Key facts
BCL-6 corepressor-like protein 1 (BCORL1) is a protein from Homo sapiens identified by UniProt accession Q5H9F3, 1785 residues long. MolForge cross-references it against 0 known binders and 318 disease associations.
- UniProt accession: Q5H9F3; gene symbol BCORL1.
- Organism: Homo sapiens.
- Length: 1785 amino acids.
- Top disease associations (Open Targets): Shukla-Vernon syndrome, neurodegenerative disease and colorectal adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BCL-6 corepressor-like protein 1 |
|---|---|
| UniProt accession | Q5H9F3 |
| Gene | BCORL1 |
| Organism | Homo sapiens |
| Length | 1785 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (318)
Diseases linked to this target (Open Targets).
- Shukla-Vernon syndrome · score 0.70
- neurodegenerative disease · score 0.52
- colorectal adenocarcinoma · score 0.41
- colon adenocarcinoma · score 0.37
- gastric adenocarcinoma · score 0.37
- breast ductal adenocarcinoma · score 0.37
- cecum adenocarcinoma · score 0.37
- lymphoid neoplasm · score 0.37
- Endometrial Endometrioid Adenocarcinoma · score 0.37
- HER2 Positive Breast Carcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9F3-F1 | alphafold | PREDICTED | 38.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9F3.
Amino-acid sequence (1785 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BCORL1?
The strongest Open Targets associations for BCORL1 are Shukla-Vernon syndrome, neurodegenerative disease, colorectal adenocarcinoma, colon adenocarcinoma and gastric adenocarcinoma.
How long is the BCORL1 protein?
The Homo sapiens BCORL1 protein (UniProt Q5H9F3) is 1785 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9F3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9F3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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