Transcription factor Dp family member 3 (TFDP3)
Homo sapiens — UniProt Q5H9I0
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor Dp family member 3 (TFDP3) is a protein from Homo sapiens identified by UniProt accession Q5H9I0, 405 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q5H9I0; gene symbol TFDP3.
- Organism: Homo sapiens.
- Length: 405 amino acids.
- Top disease associations (Open Targets): cancer, acute lymphoblastic leukemia and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor Dp family member 3 |
|---|---|
| UniProt accession | Q5H9I0 |
| Gene | TFDP3 |
| Organism | Homo sapiens |
| Length | 405 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- cancer · score 0.05
- acute lymphoblastic leukemia · score 0.04
- neoplasm · score 0.03
- melanoma · score 0.03
- breast disease · score 0.01
- invasive breast ductal carcinoma · score 0.01
- hepatocellular carcinoma · score 0.01
- invasive lobular carcinoma · score 0.01
- T-cell acute lymphoblastic leukemia · score 0.01
- breast ductal carcinoma in situ · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9I0-F1 | alphafold | PREDICTED | 67.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9I0.
Amino-acid sequence (405 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TFDP3?
The strongest Open Targets associations for TFDP3 are cancer, acute lymphoblastic leukemia, neoplasm, melanoma and breast disease.
How long is the TFDP3 protein?
The Homo sapiens TFDP3 protein (UniProt Q5H9I0) is 405 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9I0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9I0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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