Protein BEX5 (BEX5)
Homo sapiens — UniProt Q5H9J7
Data last refreshed: (UniProt release unknown)
Key facts
Protein BEX5 (BEX5) is a protein from Homo sapiens identified by UniProt accession Q5H9J7, 111 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q5H9J7; gene symbol BEX5.
- Organism: Homo sapiens.
- Length: 111 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and large cell medulloblastoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein BEX5 |
|---|---|
| UniProt accession | Q5H9J7 |
| Gene | BEX5 |
| Organism | Homo sapiens |
| Length | 111 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- glioblastoma multiforme · score 0.03
- large cell medulloblastoma · score 0.03
- ependymoma · score 0.03
- atypical teratoid rhabdoid tumor · score 0.02
- astrocytoma · score 0.02
- oligodendroglioma · score 0.02
- ovarian carcinoma · score 0.02
- medulloblastoma · score 0.02
- Tetralogy of Fallot · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9J7-F1 | alphafold | PREDICTED | 63.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9J7.
Amino-acid sequence (111 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BEX5?
The strongest Open Targets associations for BEX5 are neurodegenerative disease, glioblastoma multiforme, large cell medulloblastoma, ependymoma and atypical teratoid rhabdoid tumor.
How long is the BEX5 protein?
The Homo sapiens BEX5 protein (UniProt Q5H9J7) is 111 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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