Zinc finger matrin-type protein 1 (ZMAT1)
Homo sapiens — UniProt Q5H9K5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger matrin-type protein 1 (ZMAT1) is a protein from Homo sapiens identified by UniProt accession Q5H9K5, 638 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q5H9K5; gene symbol ZMAT1.
- Organism: Homo sapiens.
- Length: 638 amino acids.
- Top disease associations (Open Targets): neoplasm, colorectal adenocarcinoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger matrin-type protein 1 |
|---|---|
| UniProt accession | Q5H9K5 |
| Gene | ZMAT1 |
| Organism | Homo sapiens |
| Length | 638 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.06
- colorectal adenocarcinoma · score 0.04
- cancer · score 0.03
- osteosarcoma · score 0.01
- pachyonychia congenita · score 0.01
- acute myeloid leukemia · score 0.01
- ovarian carcinoma · score 0.01
- pancreatic ductal adenocarcinoma · score 0.01
- pancreatic adenocarcinoma · score 0.01
- Pick disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9K5-F1 | alphafold | PREDICTED | 51.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9K5.
Amino-acid sequence (638 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZMAT1?
The strongest Open Targets associations for ZMAT1 are neoplasm, colorectal adenocarcinoma, cancer, osteosarcoma and pachyonychia congenita.
How long is the ZMAT1 protein?
The Homo sapiens ZMAT1 protein (UniProt Q5H9K5) is 638 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9K5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9K5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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