Transcription elongation factor A protein-like 5 (TCEAL5)
Homo sapiens — UniProt Q5H9L2
Data last refreshed: (UniProt release unknown)
Key facts
Transcription elongation factor A protein-like 5 (TCEAL5) is a protein from Homo sapiens identified by UniProt accession Q5H9L2, 206 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q5H9L2; gene symbol TCEAL5.
- Organism: Homo sapiens.
- Length: 206 amino acids.
- Top disease associations (Open Targets): breast carcinoma, colorectal cancer and Ataxia-telangiectasia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription elongation factor A protein-like 5 |
|---|---|
| UniProt accession | Q5H9L2 |
| Gene | TCEAL5 |
| Organism | Homo sapiens |
| Length | 206 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.04
- colorectal cancer · score 0.02
- Ataxia-telangiectasia · score 0.02
- papillary thyroid carcinoma · score 0.01
- cancer · score 0.00
- Huntington disease · score 0.00
- Klinefelter's syndrome · score 0.00
- neoplasm · score 0.00
- myelodysplastic syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5H9L2-F1 | alphafold | PREDICTED | 58.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5H9L2.
Amino-acid sequence (206 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCEAL5?
The strongest Open Targets associations for TCEAL5 are breast carcinoma, colorectal cancer, Ataxia-telangiectasia, papillary thyroid carcinoma and cancer.
How long is the TCEAL5 protein?
The Homo sapiens TCEAL5 protein (UniProt Q5H9L2) is 206 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5H9L2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5H9L2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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