About PWWP domain-containing DNA repair factor 3B
PWWP domain-containing DNA repair factor 3B (PWWP3B) is a protein
from Homo sapiens identified by UniProt accession
Q5H9M0, 696 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (37)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.04
- glioblastoma multiforme · score 0.03
- atypical teratoid rhabdoid tumor · score 0.03
- thyroxine measurement · score 0.03
- endometrial carcinoma · score 0.03
- blood protein measurement · score 0.02
- Down syndrome · score 0.02
- medulloblastoma · score 0.02
- astrocytoma · score 0.02
- triiodothyronine measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q5H9M0.
Amino-acid sequence (696 residues)
MESEYVLCNW KDQLWPAKVL SRSETSSNSK RKKAFSLEVQ ILSLDEKIKL DSTETKILNK SQIEAIAASL GLQSEDSAPP TEETAYGRSL KVALGILNER TNLSQASTSD EEEITMLSQN VPQKQSDSPP HKKYRKDEGD LPGCLEEREN SACLLASSES DDSLYDDKSQ APTMVDTIPS EVETKSLQNS SWCETFPSLS EDNDEKENKN KIDISAVMSV HSAVKEESAC VKDEKFAPPL SPLSSDMLIM PKALKEESED TCLETLAVPS ECSAFSENIE DPGEGPSNPC LDTSQNQPSM ESEMGAAACP GSCSRECEVS FSASNPVWDY SHLMSSERNF QRLDFEELEE EGQASDKSLL PSRINLSLLD DDEEDEELPR FILHYETHPF ETGMIVWFKY QKYPFWPAVI KSIRRKERKA SVLFVEANMN SEKKGIRVNF RRLKKFDCKE KQMLVDKARE DYSESIDWCI SLICDYRVRI GCGSFTGSLL EYYAADISYP VRKETKQDTF RNKFPKLHNE DAREPMAVTS QTKKMSFQKI LPDRMKAARD RANKNLVDFI VNAKGTENHL LAIVNGTKGS RWLKSFLNAN RFTPCIETYF EDEDQLDEVV KYLQEVCNQI DQIMPTWIKD DKIKFILEVL LPEAIICSIS AVDGLDYEAA EAKYLKGPCL GYRERELFDA KIIYEKRRKA PTNEAH
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