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Fidgetin (FIGN)

Homo sapiens — UniProt Q5HY92

Gene: FIGNHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Fidgetin (FIGN) is a protein from Homo sapiens identified by UniProt accession Q5HY92, 759 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.

  • UniProt accession: Q5HY92; gene symbol FIGN.
  • Organism: Homo sapiens.
  • Length: 759 amino acids.
  • Top disease associations (Open Targets): mathematical ability, body mass index and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFidgetin
UniProt accessionQ5HY92
GeneFIGN
OrganismHomo sapiens
Length759 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (135)

Diseases linked to this target (Open Targets).

  • mathematical ability · score 0.45
  • body mass index · score 0.45
  • neurodegenerative disease · score 0.44
  • body height · score 0.44
  • diastolic blood pressure · score 0.43
  • mean arterial pressure · score 0.43
  • self reported educational attainment · score 0.40
  • cognitive function measurement · score 0.38
  • BMI-adjusted waist circumference · score 0.38
  • hypertension · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5HY92-F1alphafoldPREDICTED61.40—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HY92.

Amino-acid sequence (759 residues)

MISSTSVYGL KMQWTPEHAQ WPEQHFDITS TTRSPAHKVE AYRGHLQRTY QYAWANDDIS ALTASNLLKK YAEKYSGILE GPVDRPVLSN YSDTPSGLVN GRKNESEPWQ PSLNSEAVYP MNCVPDVITA SKAGVSSALP PADVSASIGS SPGVASNLTE PSYSSSTCGS HTVPSLHAGL PSQEYAPGYN GSYLHSTYSS QPAPALPSPH PSPLHSSGLL QPPPPPPPPP ALVPGYNGTS NLSSYSYPSA SYPPQTAVGS GYSPGGAPPP PSAYLPSGIP APTPLPPTTV PGYTYQGHGL TPIAPSALTN SSASSLKRKA FYMAGQGDMD SSYGNYSYGQ QRSTQSPMYR MPDNSISNTN RGNGFDRSAE TSSLAFKPTK QLMSSEQQRK FSSQSSRALT PPSYSTAKNS LGSRSSESFG KYTSPVMSEH GDEHRQLLSH PMQGPGLRAA TSSNHSVDEQ LKNTDTHLID LVTNEIITQG PPVDWNDIAG LDLVKAVIKE EVLWPVLRSD AFSGLTALPR SILLFGPRGT GKTLLGRCIA SQLGATFFKI AGSGLVAKWL GEAEKIIHAS FLVARCRQPS VIFVSDIDML LSSQVNEEHS PVSRMRTEFL MQLDTVLTSA EDQIVVICAT SKPEEIDESL RRYFMKRLLI PLPDSTARHQ IIVQLLSQHN YCLNDKEFAL LVQRTEGFSG LDVAHLCQEA VVGPLHAMPA TDLSAIMPSQ LRPVTYQDFE NAFCKIQPSI SQKELDMYVE WNKMFGCSQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FIGN?

The strongest Open Targets associations for FIGN are mathematical ability, body mass index, neurodegenerative disease, body height and diastolic blood pressure.

How long is the FIGN protein?

The Homo sapiens FIGN protein (UniProt Q5HY92) is 759 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5HY92
GeneFIGN
OrganismHomo sapiens
Length759
Binders0
Diseases135
View on UniProt