Uncharacterized bromodomain-containing protein 10 (BRD10)

Homo sapiens — UniProt Q5HYC2

Gene: BRD10Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Uncharacterized bromodomain-containing protein 10 (BRD10) is a protein from Homo sapiens identified by UniProt accession Q5HYC2, 2103 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

UniProt accession: Q5HYC2; gene symbol BRD10.
Organism: Homo sapiens.
Length: 2103 amino acids.
Top disease associations (Open Targets): PHF-tau measurement, multiple sclerosis and skin pigmentation.
3D structure: AlphaFold model available.

Target properties

Protein name	Uncharacterized bromodomain-containing protein 10
UniProt accession	Q5HYC2
Gene	BRD10
Organism	Homo sapiens
Length	2103 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

PHF-tau measurement · score 0.35
multiple sclerosis · score 0.33
skin pigmentation · score 0.27
appendicular lean mass · score 0.27
asthma · score 0.24
hair colour measurement · score 0.24
glycine measurement · score 0.23
hair color · score 0.22
Eczematoid dermatitis · score 0.19
protein measurement · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5HYC2-F1	alphafold	PREDICTED	44.88	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYC2.

Amino-acid sequence (2103 residues)

MSVPGTPGAM EPAGEEERPP PAAEGEDDEE EVAAAAQTSG PAHGRSASSL EDADDQEEEM EAMVIGGGCC KEQELTYELQ QGYRILGEFL QEKHRGLTAP FLQPLGGVAT AEEEVAEGPR SGGRGGRAFP QQPGQGMCLL QMEEKFASGQ YGGITEFVAD FRLMLETCYR LHGVDHWISK QGQKLEMMLE QKLALLSRHL REKTTIAVTS RGYYGLEDEK GTACTSTRRR STPRSLAGLT SGVFESIMVQ VLRQEEQLRA KEEKRLREQE RKEAEEASQK EIEEWERKLL AQAAPTCMET MWEIPAIGHF LCLAQQILNL PEIVFYELER CLLMPQCNAF LSKIMTSLLS PPHRRPTLHR RPTLPYRTWE AALRQKVQQW YTAVGQTENP DNCAEKLGLC PQFFKVLGEV NPLEEKPFHE LPFYQKVWLL KGLCDFVYET QKEVQDAVLG QPIHECREVI LGYDYLENAY VHFPQFCGAD VRIYKQRPFQ APEFPIPPIK IQRVPRIKLE KLKCDYVSTS NGEHRCSRDS LPSSFKKEQE NNFDPACCPA KMILDNHDIS VEMGVKSNYE IRIRRPCEIK KTDCCKENLE KPRSPGEVTG FGEPLSPGEI RFIENQEKYG EASRIKIEPS PLKENTLKSC QIHVNGSHSD HPEINCHKVV RDILLEQSLQ SHKKLKLTKM RAKKKKKKKK KLKDVLNENL QRKREGLHSL AFKSYKPEIQ NKLLIIKKKA KHKKHKSGKK SVSKKAITKK RKTVIKSPTV PEFQLICTNL DELRELITKI ENELKDLENS RKKSGKWYHR RQAVKELHST LIRLLNELLP WEPKLMKAFQ RNRSRLKKDY DDFRRQPDHD TFNRELWTTD EGEGDLGKDS PKGEISKSID STEPLDILEK DHFDSDDMKL SEIDFPMARS KLLKKELPSK DLPKTLLKTL KRQSKQTDYV DDSTKELSPR KKAKLSTNET TVENLESDVQ IDCFSESKHT EPSFPESFAS LDSVPVSTLQ KGTKPIQALL AKNIGNKVTL TNQLPPSTGR NALAVEKPVL SPPEASPIKP ALTCHTNTKG PLQMVYKMPC GQWLPIDLQN SSVKIQVQPM VDPKTGEKIM QQVLILPKNF VIQHKEGKAV AKEVPPLQQK GTEQHCSSFP QTTNINSSLA SVFVNSPGTV STQLPNTAFN KTITPLSNIS SARPQPLSPV TSVSNLLTPS VKTSQSEAGK AKNAVSAATF SLPSASPTIS STGQPLSSTT TLNGSTNPGS SFNCFAQQTA DSSEAKQELK TVCIRDSQSI LVRTRGGNTG VVKVQTNPDQ NSPNTVSSSS VFTFAPQLQA FLVPKSTTSS SAFSPVAGTT TTSSLSPFSQ TPTSVSIPAS FAPSMGKNLK LTLGHTTGSG DLGHVIDKTS HMPSSPLKSS ICSSTLLPST TSSSVSVISI SAANFGQNNA NIIHTPTKQQ QVDYITKSYP VTRSEATAAT NGDVISGTPV QKLMLVSAPS ILSSGNGTAI NMTPALTSTG VSAQKLVFIN APVPSGTSTP TLVAESLKQT LPPPLHKAYV KTPEQPQIVL IPSTVGTPIK INSSPAVSQI KDVKIGLNIG QAIVNTSGTV PAIPSINILQ NVTPKGEDKS SKGYILPLST SGNSVPVSSN FVSQNITPVN ESVVSSARAV NVLSVTGANL SLGSFPVTSA SASAGAQPPV LVSGNDTSSR IMPILSNRLC SSSLGNTVAI STVKTGHLAS SVLISTTQPV VSPKCLTSAL QIPVTVALPT PATTSPKIIN TVPHSAAVPG ATRSVSISKR QSRTSLQFHS PGISTTVPTN VNTNKPQTEL SSLSTSPGKI TNTSNFASLP NQQALVKTPS YSSAPGGTTI HTASAPSNVT SLVGSQFSEP CIQQKIVINT STPLAPGTQI MINGTRFIVP PQGLGAGSHV LLISTNPKYG APLVLNSGQG IQSTPIDNSA QKITLASNNS LSGQPLQHPL RSPTKFINSF GNASSIPTVH TSPQLINTTA KVPVPPPVPT VSLTSVIKSP ATLLAKTSLV SAICPSNPPL PSSTSVFHLD PPVKKLLVSP EGAILNTINT PASKVSSLSP SLSQIVVSAS RSPASVFPAF QSSGLEKPDR AAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with BRD10?

The strongest Open Targets associations for BRD10 are PHF-tau measurement, multiple sclerosis, skin pigmentation, appendicular lean mass and asthma.

How long is the BRD10 protein?

The Homo sapiens BRD10 protein (UniProt Q5HYC2) is 2103 amino acids long.

Browse: Targets: B · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5HYC2 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5HYC2 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.