Metaxin-3 (MTX3)
Homo sapiens — UniProt Q5HYI7
Data last refreshed: (UniProt release unknown)
Key facts
Metaxin-3 (MTX3) is a protein from Homo sapiens identified by UniProt accession Q5HYI7, 312 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q5HYI7; gene symbol MTX3.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): Varicose veins, protein measurement and refractive error measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Metaxin-3 |
|---|---|
| UniProt accession | Q5HYI7 |
| Gene | MTX3 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- Varicose veins · score 0.27
- protein measurement · score 0.25
- refractive error measurement · score 0.13
- intraocular pressure measurement · score 0.10
- blood protein measurement · score 0.10
- smoking status measurement · score 0.09
- appendicular lean mass · score 0.08
- drug use measurement · score 0.08
- wellbeing measurement · score 0.08
- alcohol consumption measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5HYI7-F1 | alphafold | PREDICTED | 84.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYI7.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MTX3?
The strongest Open Targets associations for MTX3 are Varicose veins, protein measurement, refractive error measurement, intraocular pressure measurement and blood protein measurement.
How long is the MTX3 protein?
The Homo sapiens MTX3 protein (UniProt Q5HYI7) is 312 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5HYI7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5HYI7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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