Rab-like protein 3 (RABL3)
Homo sapiens — UniProt Q5HYI8
Data last refreshed: (UniProt release unknown)
Key facts
Rab-like protein 3 (RABL3) is a protein from Homo sapiens identified by UniProt accession Q5HYI8, 236 residues long. MolForge cross-references it against 1 known binders and 35 disease associations.
- UniProt accession: Q5HYI8; gene symbol RABL3.
- Organism: Homo sapiens.
- Length: 236 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Malignant Pancreatic Neoplasm and familial pancreatic carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rab-like protein 3 |
|---|---|
| UniProt accession | Q5HYI8 |
| Gene | RABL3 |
| Organism | Homo sapiens |
| Length | 236 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- Malignant Pancreatic Neoplasm · score 0.42
- familial pancreatic carcinoma · score 0.37
- lysosomal storage disease · score 0.10
- Okt4 epitope deficiency · score 0.07
- hepatocellular carcinoma · score 0.04
- reticular dysgenesis · score 0.04
- Hodgkins lymphoma · score 0.04
- classic Hodgkin lymphoma · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5HYI8-F1 | alphafold | PREDICTED | 80.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYI8.
Amino-acid sequence (236 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RABL3?
The strongest Open Targets associations for RABL3 are neurodegenerative disease, Malignant Pancreatic Neoplasm, familial pancreatic carcinoma, lysosomal storage disease and Okt4 epitope deficiency.
How long is the RABL3 protein?
The Homo sapiens RABL3 protein (UniProt Q5HYI8) is 236 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5HYI8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5HYI8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.