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Protein FAM76B (FAM76B)

Homo sapiens — UniProt Q5HYJ3

Gene: FAM76BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM76B (FAM76B) is a protein from Homo sapiens identified by UniProt accession Q5HYJ3, 339 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

  • UniProt accession: Q5HYJ3; gene symbol FAM76B.
  • Organism: Homo sapiens.
  • Length: 339 amino acids.
  • Top disease associations (Open Targets): body height, Eczematoid dermatitis and allergic rhinitis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM76B
UniProt accessionQ5HYJ3
GeneFAM76B
OrganismHomo sapiens
Length339 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (80)

Diseases linked to this target (Open Targets).

  • body height · score 0.29
  • Eczematoid dermatitis · score 0.27
  • allergic rhinitis · score 0.26
  • reticulocyte count · score 0.25
  • asthma · score 0.24
  • Red cell distribution width · score 0.24
  • seasonal allergic rhinitis · score 0.22
  • appendicular lean mass · score 0.22
  • sex hormone-binding globulin measurement · score 0.21
  • hypothyroidism · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5HYJ3-F1alphafoldPREDICTED76.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYJ3.

Amino-acid sequence (339 residues)

MAASALYACT KCTQRYPFEE LSQGQQLCKE CRIAHPIVKC TYCRSEFQQE SKTNTICKKC AQNVKQFGTP KPCQYCNIIA AFIGTKCQRC TNSEKKYGPP QTCEQCKQQC AFDRKEEGRR KVDGKLLCWL CTLSYKRVLQ KTKEQRKSLG SSHSNSSSSS LTEKDQHHPK HHHHHHHHHH RHSSSHHKIS NLSPEEEQGL WKQSHKSSAT IQNETPKKKP KLESKPSNGD SSSINQSADS GGTDNFVLIS QLKEEVMSLK RLLQQRDQTI LEKDKKLTEL KADFQYQESN LRTKMNSMEK AHKETVEQLQ AKNRELLKQV AALSKGKKFD KSGSILTSP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM76B?

The strongest Open Targets associations for FAM76B are body height, Eczematoid dermatitis, allergic rhinitis, reticulocyte count and asthma.

How long is the FAM76B protein?

The Homo sapiens FAM76B protein (UniProt Q5HYJ3) is 339 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5HYJ3
GeneFAM76B
OrganismHomo sapiens
Length339
Binders0
Diseases80
View on UniProt