SH3 domain-containing protein 19 (SH3D19)
Homo sapiens — UniProt Q5HYK7
Data last refreshed: (UniProt release unknown)
Key facts
SH3 domain-containing protein 19 (SH3D19) is a protein from Homo sapiens identified by UniProt accession Q5HYK7, 790 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q5HYK7; gene symbol SH3D19.
- Organism: Homo sapiens.
- Length: 790 amino acids.
- Top disease associations (Open Targets): leukocyte count, Age-related cataract and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SH3 domain-containing protein 19 |
|---|---|
| UniProt accession | Q5HYK7 |
| Gene | SH3D19 |
| Organism | Homo sapiens |
| Length | 790 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.32
- Age-related cataract · score 0.21
- prostate carcinoma · score 0.18
- neutrophil count · score 0.18
- essential tremor · score 0.11
- drug-induced liver injury · score 0.06
- self reported educational attainment · score 0.06
- cognitive function measurement · score 0.06
- lean body mass · score 0.05
- platelet count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5HYK7-F1 | alphafold | PREDICTED | 58.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYK7.
Amino-acid sequence (790 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SH3D19?
The strongest Open Targets associations for SH3D19 are leukocyte count, Age-related cataract, prostate carcinoma, neutrophil count and essential tremor.
How long is the SH3D19 protein?
The Homo sapiens SH3D19 protein (UniProt Q5HYK7) is 790 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5HYK7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5HYK7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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