Zinc finger protein 667 (ZNF667)
Homo sapiens — UniProt Q5HYK9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 667 (ZNF667) is a protein from Homo sapiens identified by UniProt accession Q5HYK9, 610 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q5HYK9; gene symbol ZNF667.
- Organism: Homo sapiens.
- Length: 610 amino acids.
- Top disease associations (Open Targets): ulcerative colitis, esophageal squamous cell carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 667 |
|---|---|
| UniProt accession | Q5HYK9 |
| Gene | ZNF667 |
| Organism | Homo sapiens |
| Length | 610 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- ulcerative colitis · score 0.13
- esophageal squamous cell carcinoma · score 0.10
- neoplasm · score 0.08
- laryngeal squamous cell carcinoma · score 0.08
- acute myeloid leukemia · score 0.08
- calf circumference measurement · score 0.06
- low density lipoprotein cholesterol measurement · score 0.05
- Down syndrome · score 0.05
- cancer · score 0.04
- alkaline phosphatase measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5HYK9-F1 | alphafold | PREDICTED | 69.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYK9.
Amino-acid sequence (610 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF667?
The strongest Open Targets associations for ZNF667 are ulcerative colitis, esophageal squamous cell carcinoma, neoplasm, laryngeal squamous cell carcinoma and acute myeloid leukemia.
How long is the ZNF667 protein?
The Homo sapiens ZNF667 protein (UniProt Q5HYK9) is 610 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5HYK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5HYK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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