Retrotransposon Gag-like protein 5 (RTL5)
Homo sapiens — UniProt Q5HYW3
Data last refreshed: (UniProt release unknown)
Key facts
Retrotransposon Gag-like protein 5 (RTL5) is a protein from Homo sapiens identified by UniProt accession Q5HYW3, 569 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q5HYW3; gene symbol RTL5.
- Organism: Homo sapiens.
- Length: 569 amino acids.
- Top disease associations (Open Targets): kidney disease, nephronophthisis 3 and colorectal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Retrotransposon Gag-like protein 5 |
|---|---|
| UniProt accession | Q5HYW3 |
| Gene | RTL5 |
| Organism | Homo sapiens |
| Length | 569 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- kidney disease · score 0.03
- nephronophthisis 3 · score 0.03
- colorectal cancer · score 0.01
- infect · score 0.01
- infection · score 0.01
- chronic myelogenous leukemia · score 0.00
- small cell lung carcinoma · score 0.00
- hyperinsulinemic hypoglycemia, familial, 4 · score 0.00
- parasitic infection · score 0.00
- viral disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5HYW3-F1 | alphafold | PREDICTED | 63.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5HYW3.
Amino-acid sequence (569 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RTL5?
The strongest Open Targets associations for RTL5 are kidney disease, nephronophthisis 3, colorectal cancer, infect and infection.
How long is the RTL5 protein?
The Homo sapiens RTL5 protein (UniProt Q5HYW3) is 569 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5HYW3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5HYW3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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