Peroxisomal biogenesis factor 39 (PEX39)
Homo sapiens — UniProt Q5I0X4
Data last refreshed: (UniProt release unknown)
Key facts
Peroxisomal biogenesis factor 39 (PEX39) is a protein from Homo sapiens identified by UniProt accession Q5I0X4, 101 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q5I0X4; gene symbol PEX39.
- Organism: Homo sapiens.
- Length: 101 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peroxisomal biogenesis factor 39 |
|---|---|
| UniProt accession | Q5I0X4 |
| Gene | PEX39 |
| Organism | Homo sapiens |
| Length | 101 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- mean platelet volume · score 0.16
- platelet count · score 0.11
- mediator of RNA polymerase II transcription subunit 1 measurement · score 0.06
- smoking status measurement · score 0.05
- substance abuse · score 0.05
- antisocial behaviour measurement · score 0.05
- attention deficit hyperactivity disorder · score 0.05
- hematocrit · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5I0X4-F1 | alphafold | PREDICTED | 70.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5I0X4.
Amino-acid sequence (101 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PEX39?
The strongest Open Targets associations for PEX39 are neurodegenerative disease, mean platelet volume, platelet count, mediator of RNA polymerase II transcription subunit 1 measurement and smoking status measurement.
How long is the PEX39 protein?
The Homo sapiens PEX39 protein (UniProt Q5I0X4) is 101 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5I0X4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5I0X4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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