Tetratricopeptide repeat protein 32 (TTC32)
Homo sapiens — UniProt Q5I0X7
Data last refreshed: (UniProt release unknown)
Key facts
Tetratricopeptide repeat protein 32 (TTC32) is a protein from Homo sapiens identified by UniProt accession Q5I0X7, 151 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q5I0X7; gene symbol TTC32.
- Organism: Homo sapiens.
- Length: 151 amino acids.
- Top disease associations (Open Targets): coronary artery disease, creatinine measurement and myocardial infarction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetratricopeptide repeat protein 32 |
|---|---|
| UniProt accession | Q5I0X7 |
| Gene | TTC32 |
| Organism | Homo sapiens |
| Length | 151 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.33
- creatinine measurement · score 0.30
- myocardial infarction · score 0.29
- Vasodilators used in cardiac diseases use measurement · score 0.28
- angina pectoris · score 0.28
- sitting height measurement · score 0.27
- heel bone mineral density · score 0.26
- synophrys measurement · score 0.23
- heart disease · score 0.21
- coronary atherosclerosis · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5I0X7-F1 | alphafold | PREDICTED | 91.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5I0X7.
Amino-acid sequence (151 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTC32?
The strongest Open Targets associations for TTC32 are coronary artery disease, creatinine measurement, myocardial infarction, Vasodilators used in cardiac diseases use measurement and angina pectoris.
How long is the TTC32 protein?
The Homo sapiens TTC32 protein (UniProt Q5I0X7) is 151 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5I0X7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5I0X7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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