Polyadenylate-binding protein 1-like 2 (PABPC1L2A)
Homo sapiens — UniProt Q5JQF8
Data last refreshed: (UniProt release unknown)
Key facts
Polyadenylate-binding protein 1-like 2 (PABPC1L2A) is a protein from Homo sapiens identified by UniProt accession Q5JQF8, 200 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q5JQF8; gene symbol PABPC1L2A.
- Organism: Homo sapiens.
- Length: 200 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, central nervous system cancer and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyadenylate-binding protein 1-like 2 |
|---|---|
| UniProt accession | Q5JQF8 |
| Gene | PABPC1L2A |
| Organism | Homo sapiens |
| Length | 200 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- central nervous system cancer · score 0.04
- Alzheimer disease · score 0.00
- oligodendroglioma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JQF8-F1 | alphafold | PREDICTED | 90.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JQF8.
Amino-acid sequence (200 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PABPC1L2A?
The strongest Open Targets associations for PABPC1L2A are neurodegenerative disease, central nervous system cancer, Alzheimer disease and oligodendroglioma.
How long is the PABPC1L2A protein?
The Homo sapiens PABPC1L2A protein (UniProt Q5JQF8) is 200 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JQF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JQF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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