Krueppel-like factor 17 (KLF17)
Homo sapiens — UniProt Q5JT82
Data last refreshed: (UniProt release unknown)
Key facts
Krueppel-like factor 17 (KLF17) is a protein from Homo sapiens identified by UniProt accession Q5JT82, 389 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q5JT82; gene symbol KLF17.
- Organism: Homo sapiens.
- Length: 389 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, multiple sclerosis and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Krueppel-like factor 17 |
|---|---|
| UniProt accession | Q5JT82 |
| Gene | KLF17 |
| Organism | Homo sapiens |
| Length | 389 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- multiple sclerosis · score 0.26
- lysosomal storage disease · score 0.26
- Alzheimer disease · score 0.26
- Parkinson disease · score 0.26
- drug use measurement · score 0.11
- neuroticism measurement · score 0.09
- cancer · score 0.09
- self reported educational attainment · score 0.07
- oral squamous cell carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JT82-F1 | alphafold | PREDICTED | 53.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JT82.
Amino-acid sequence (389 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLF17?
The strongest Open Targets associations for KLF17 are neurodegenerative disease, multiple sclerosis, lysosomal storage disease, Alzheimer disease and Parkinson disease.
How long is the KLF17 protein?
The Homo sapiens KLF17 protein (UniProt Q5JT82) is 389 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JT82 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JT82 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.