Tight junction-associated protein 1 (TJAP1)
Homo sapiens — UniProt Q5JTD0
Data last refreshed: (UniProt release unknown)
Key facts
Tight junction-associated protein 1 (TJAP1) is a protein from Homo sapiens identified by UniProt accession Q5JTD0, 557 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q5JTD0; gene symbol TJAP1.
- Organism: Homo sapiens.
- Length: 557 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, hematocrit and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tight junction-associated protein 1 |
|---|---|
| UniProt accession | Q5JTD0 |
| Gene | TJAP1 |
| Organism | Homo sapiens |
| Length | 557 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.03
- hematocrit · score 0.02
- infect · score 0.02
- infection · score 0.02
- erythrocyte count · score 0.02
- red blood cell density measurement · score 0.02
- mean corpuscular hemoglobin concentration · score 0.02
- pneumonia · score 0.01
- bathing suit ichthyosis · score 0.01
- bacterial urinary tract infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JTD0-F1 | alphafold | PREDICTED | 61.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JTD0.
Amino-acid sequence (557 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TJAP1?
The strongest Open Targets associations for TJAP1 are hemoglobin measurement, hematocrit, infect, infection and erythrocyte count.
How long is the TJAP1 protein?
The Homo sapiens TJAP1 protein (UniProt Q5JTD0) is 557 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JTD0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JTD0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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