Leucine-rich repeat-containing protein 73 (LRRC73)
Homo sapiens — UniProt Q5JTD7
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 73 (LRRC73) is a protein from Homo sapiens identified by UniProt accession Q5JTD7, 316 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q5JTD7; gene symbol LRRC73.
- Organism: Homo sapiens.
- Length: 316 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, glioblastoma multiforme and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 73 |
|---|---|
| UniProt accession | Q5JTD7 |
| Gene | LRRC73 |
| Organism | Homo sapiens |
| Length | 316 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.05
- glioblastoma multiforme · score 0.03
- reticulocyte count · score 0.02
- hemoglobin measurement · score 0.02
- astrocytoma · score 0.01
- oligodendroglioma · score 0.01
- ulcerative colitis · score 0.01
- Colon Sessile Serrated Adenoma/Polyp · score 0.00
- cerebral infarction · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JTD7-F1 | alphafold | PREDICTED | 84.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JTD7.
Amino-acid sequence (316 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC73?
The strongest Open Targets associations for LRRC73 are mean corpuscular hemoglobin concentration, glioblastoma multiforme, reticulocyte count, hemoglobin measurement and astrocytoma.
How long is the LRRC73 protein?
The Homo sapiens LRRC73 protein (UniProt Q5JTD7) is 316 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JTD7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JTD7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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