WD repeat-containing protein 38 (WDR38)
Homo sapiens — UniProt Q5JTN6
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 38 (WDR38) is a protein from Homo sapiens identified by UniProt accession Q5JTN6, 314 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q5JTN6; gene symbol WDR38.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, testosterone measurement and grip strength measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 38 |
|---|---|
| UniProt accession | Q5JTN6 |
| Gene | WDR38 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- testosterone measurement · score 0.11
- grip strength measurement · score 0.10
- forced expiratory volume · score 0.08
- BMI-adjusted waist-hip ratio · score 0.06
- vital capacity · score 0.05
- waist-hip ratio · score 0.05
- central nervous system cancer · score 0.04
- venous thromboembolism · score 0.02
- hair colour measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JTN6-F1 | alphafold | PREDICTED | 87.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JTN6.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR38?
The strongest Open Targets associations for WDR38 are neurodegenerative disease, testosterone measurement, grip strength measurement, forced expiratory volume and BMI-adjusted waist-hip ratio.
How long is the WDR38 protein?
The Homo sapiens WDR38 protein (UniProt Q5JTN6) is 314 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JTN6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JTN6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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