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Uncharacterized protein C9orf152 (C9orf152)

Homo sapiens — UniProt Q5JTZ5

Gene: C9orf152Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C9orf152 (C9orf152) is a protein from Homo sapiens identified by UniProt accession Q5JTZ5, 239 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q5JTZ5; gene symbol C9orf152.
  • Organism: Homo sapiens.
  • Length: 239 amino acids.
  • Top disease associations (Open Targets): urate measurement, bone density and body height.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C9orf152
UniProt accessionQ5JTZ5
GeneC9orf152
OrganismHomo sapiens
Length239 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • urate measurement · score 0.40
  • bone density · score 0.40
  • body height · score 0.16
  • platelet component distribution width · score 0.11
  • mean platelet volume · score 0.10
  • erythrocyte count · score 0.10
  • vital capacity · score 0.09
  • blood urea nitrogen measurement · score 0.08
  • metabolite measurement · score 0.07
  • neutrophil count · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5JTZ5-F1alphafoldPREDICTED57.66—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JTZ5.

Amino-acid sequence (239 residues)

MEGLPCPCPA LPHFWQLRSH LMAEGSRTQA PGKGPPLSIQ FLRAQYEGLK RQQRTQAHLL VLPKGGNTPA PAESMVNAVW INKERRSSLS LEEADSEVEG RLEEAAQGCL QAPKSPWHTH LEMHCLVQTS PQDTSHQVHH RGKLVGSDQR LPPEGDTHLF ETNQMTQQGT GIPEAAQLPC QVGNTQTKAV ESGLKFSTQC PLSIKNPHRS GKPAYYPFPQ RKTPRISQAA RNLGLYGSA

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C9orf152?

The strongest Open Targets associations for C9orf152 are urate measurement, bone density, body height, platelet component distribution width and mean platelet volume.

How long is the C9orf152 protein?

The Homo sapiens C9orf152 protein (UniProt Q5JTZ5) is 239 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5JTZ5
GeneC9orf152
OrganismHomo sapiens
Length239
Binders0
Diseases44
View on UniProt