Torsin-2A (TOR2A)
Homo sapiens — UniProt Q5JU69
Data last refreshed: (UniProt release unknown)
Key facts
Torsin-2A (TOR2A) is a protein from Homo sapiens identified by UniProt accession Q5JU69, 321 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q5JU69; gene symbol TOR2A.
- Organism: Homo sapiens.
- Length: 321 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Torsin-2A |
|---|---|
| UniProt accession | Q5JU69 |
| Gene | TOR2A |
| Organism | Homo sapiens |
| Length | 321 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.15
- mathematical ability · score 0.12
- pulse pressure measurement · score 0.03
- preeclampsia · score 0.03
- serum metabolite measurement · score 0.03
- systolic blood pressure · score 0.03
- blood protein measurement · score 0.03
- prostate carcinoma · score 0.02
- metabolic syndrome · score 0.01
- neuroblastoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JU69-F1 | alphafold | PREDICTED | 87.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JU69.
Amino-acid sequence (321 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TOR2A?
The strongest Open Targets associations for TOR2A are self reported educational attainment, mathematical ability, pulse pressure measurement, preeclampsia and serum metabolite measurement.
How long is the TOR2A protein?
The Homo sapiens TOR2A protein (UniProt Q5JU69) is 321 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JU69 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JU69 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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