Protein FAM78A (FAM78A)
Homo sapiens — UniProt Q5JUQ0
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM78A (FAM78A) is a protein from Homo sapiens identified by UniProt accession Q5JUQ0, 283 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q5JUQ0; gene symbol FAM78A.
- Organism: Homo sapiens.
- Length: 283 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, electrocardiography and PR interval.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM78A |
|---|---|
| UniProt accession | Q5JUQ0 |
| Gene | FAM78A |
| Organism | Homo sapiens |
| Length | 283 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- electrocardiography · score 0.05
- PR interval · score 0.05
- mean platelet volume · score 0.04
- platelet count · score 0.03
- lean body mass · score 0.02
- fat body mass · score 0.02
- renal cell carcinoma · score 0.01
- neoplasm · score 0.01
- chronic interstitial cystitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JUQ0-F1 | alphafold | PREDICTED | 89.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JUQ0.
Amino-acid sequence (283 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM78A?
The strongest Open Targets associations for FAM78A are neurodegenerative disease, electrocardiography, PR interval, mean platelet volume and platelet count.
How long is the FAM78A protein?
The Homo sapiens FAM78A protein (UniProt Q5JUQ0) is 283 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JUQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JUQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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