PCI domain-containing protein 2 (PCID2)

About PCI domain-containing protein 2

PCI domain-containing protein 2 (PCID2) is a protein from Homo sapiens identified by UniProt accession Q5JVF3, 399 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	PCI domain-containing protein 2
UniProt accession	Q5JVF3
Gene	PCID2
Organism	Homo sapiens
Length	399 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
mean corpuscular volume · score 0.29
protein measurement · score 0.25
blood protein measurement · score 0.23
mean corpuscular hemoglobin · score 0.22
mean corpuscular hemoglobin concentration · score 0.21
dual specificity mitogen-activated protein kinase kinase 2 measurement · score 0.18
Red cell distribution width · score 0.15
reticulocyte measurement · score 0.12
body height · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5JVF3-F1	alphafold	PREDICTED	95.54	—

Amino-acid sequence (399 residues)

MAHITINQYL QQVYEAIDSR DGASCAELVS FKHPHVANPR LQMASPEEKC QQVLEPPYDE MFAAHLRCTY AVGNHDFIEA YKCQTVIVQS FLRAFQAHKE ENWALPVMYA VALDLRVFAN NADQQLVKKG KSKVGDMLEK AAELLMSCFR VCASDTRAGI EDSKKWGMLF LVNQLFKIYF KINKLHLCKP LIRAIDSSNL KDDYSTAQRV TYKYYVGRKA MFDSDFKQAE EYLSFAFEHC HRSSQKNKRM ILIYLLPVKM LLGHMPTVEL LKKYHLMQFA EVTRAVSEGN LLLLHEALAK HEAFFIRCGI FLILEKLKII TYRNLFKKVY LLLKTHQLSL DAFLVALKFM QVEDVDIDEV QCILANLIYM GHVKGYISHQ HQKLVVSKQN PFPPLSTVC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards