Zinc finger protein 484 (ZNF484)
Homo sapiens — UniProt Q5JVG2
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 484 (ZNF484) is a protein from Homo sapiens identified by UniProt accession Q5JVG2, 852 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q5JVG2; gene symbol ZNF484.
- Organism: Homo sapiens.
- Length: 852 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 484 |
|---|---|
| UniProt accession | Q5JVG2 |
| Gene | ZNF484 |
| Organism | Homo sapiens |
| Length | 852 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.46
- bone quantitative ultrasound measurement · score 0.34
- body height · score 0.29
- appendicular lean mass · score 0.08
- platelet count · score 0.07
- mean platelet volume · score 0.06
- platelet crit · score 0.04
- platelet component distribution width · score 0.04
- coronary artery disease · score 0.03
- lean body mass · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JVG2-F1 | alphafold | PREDICTED | 60.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JVG2.
Amino-acid sequence (852 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF484?
The strongest Open Targets associations for ZNF484 are heel bone mineral density, bone quantitative ultrasound measurement, body height, appendicular lean mass and platelet count.
How long is the ZNF484 protein?
The Homo sapiens ZNF484 protein (UniProt Q5JVG2) is 852 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JVG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JVG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.