Zinc finger protein 506 (ZNF506)
Homo sapiens — UniProt Q5JVG8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 506 (ZNF506) is a protein from Homo sapiens identified by UniProt accession Q5JVG8, 444 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q5JVG8; gene symbol ZNF506.
- Organism: Homo sapiens.
- Length: 444 amino acids.
- Top disease associations (Open Targets): esterified cholesterol measurement, very low density lipoprotein cholesterol measurement and serum metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 506 |
|---|---|
| UniProt accession | Q5JVG8 |
| Gene | ZNF506 |
| Organism | Homo sapiens |
| Length | 444 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- esterified cholesterol measurement · score 0.28
- very low density lipoprotein cholesterol measurement · score 0.28
- serum metabolite measurement · score 0.28
- neurodegenerative disease · score 0.22
- Down syndrome · score 0.02
- erythrocyte count · score 0.02
- infect · score 0.02
- infection · score 0.02
- cancer · score 0.01
- acute myeloid leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JVG8-F1 | alphafold | PREDICTED | 67.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JVG8.
Amino-acid sequence (444 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF506?
The strongest Open Targets associations for ZNF506 are esterified cholesterol measurement, very low density lipoprotein cholesterol measurement, serum metabolite measurement, neurodegenerative disease and Down syndrome.
How long is the ZNF506 protein?
The Homo sapiens ZNF506 protein (UniProt Q5JVG8) is 444 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JVG8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JVG8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.