Intracellular hyaluronan-binding protein 4 (HABP4)
Homo sapiens — UniProt Q5JVS0
Data last refreshed: (UniProt release unknown)
Key facts
Intracellular hyaluronan-binding protein 4 (HABP4) is a protein from Homo sapiens identified by UniProt accession Q5JVS0, 413 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q5JVS0; gene symbol HABP4.
- Organism: Homo sapiens.
- Length: 413 amino acids.
- Top disease associations (Open Targets): body height, mathematical ability and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Intracellular hyaluronan-binding protein 4 |
|---|---|
| UniProt accession | Q5JVS0 |
| Gene | HABP4 |
| Organism | Homo sapiens |
| Length | 413 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- body height · score 0.42
- mathematical ability · score 0.38
- neurodegenerative disease · score 0.37
- intelligence · score 0.36
- lean body mass · score 0.35
- lymphocyte count · score 0.33
- self reported educational attainment · score 0.33
- cognitive function measurement · score 0.33
- appendicular lean mass · score 0.32
- platelet count · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JVS0-F1 | alphafold | PREDICTED | 55.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JVS0.
Amino-acid sequence (413 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HABP4?
The strongest Open Targets associations for HABP4 are body height, mathematical ability, neurodegenerative disease, intelligence and lean body mass.
How long is the HABP4 protein?
The Homo sapiens HABP4 protein (UniProt Q5JVS0) is 413 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JVS0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JVS0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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