Actin-like protein 10 (ACTL10)
Homo sapiens — UniProt Q5JWF8
Data last refreshed: (UniProt release unknown)
Key facts
Actin-like protein 10 (ACTL10) is a protein from Homo sapiens identified by UniProt accession Q5JWF8, 245 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q5JWF8; gene symbol ACTL10.
- Organism: Homo sapiens.
- Length: 245 amino acids.
- Top disease associations (Open Targets): acute myeloid leukemia, skin pigmentation and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-like protein 10 |
|---|---|
| UniProt accession | Q5JWF8 |
| Gene | ACTL10 |
| Organism | Homo sapiens |
| Length | 245 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.07
- skin pigmentation · score 0.04
- lean body mass · score 0.02
- whole body water mass · score 0.02
- skin aging measurement · score 0.02
- fat body mass · score 0.02
- septic shock · score 0.01
- myeloid leukemia · score 0.01
- infection · score 0.00
- infect · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JWF8-F1 | alphafold | PREDICTED | 93.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JWF8.
Amino-acid sequence (245 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACTL10?
The strongest Open Targets associations for ACTL10 are acute myeloid leukemia, skin pigmentation, lean body mass, whole body water mass and skin aging measurement.
How long is the ACTL10 protein?
The Homo sapiens ACTL10 protein (UniProt Q5JWF8) is 245 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JWF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JWF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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