Protein FAM209B (FAM209B)
Homo sapiens — UniProt Q5JX69
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM209B (FAM209B) is a protein from Homo sapiens identified by UniProt accession Q5JX69, 171 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.
- UniProt accession: Q5JX69; gene symbol FAM209B.
- Organism: Homo sapiens.
- Length: 171 amino acids.
- Top disease associations (Open Targets): azoospermia, male infertility with teratozoospermia due to single gene mutation and hair color.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM209B |
|---|---|
| UniProt accession | Q5JX69 |
| Gene | FAM209B |
| Organism | Homo sapiens |
| Length | 171 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (106)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- hair color · score 0.10
- hair shape measurement · score 0.10
- spermatogenic failure 42 · score 0.09
- spermatogenic failure 24 · score 0.08
- spermatogenic failure 72 · score 0.08
- spermatogenic failure 51 · score 0.08
- spermatogenic failure 18 · score 0.08
- spermatogenic failure 46 · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JX69-F1 | alphafold | PREDICTED | 58.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JX69.
Amino-acid sequence (171 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM209B?
The strongest Open Targets associations for FAM209B are azoospermia, male infertility with teratozoospermia due to single gene mutation, hair color, hair shape measurement and spermatogenic failure 42.
How long is the FAM209B protein?
The Homo sapiens FAM209B protein (UniProt Q5JX69) is 171 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JX69 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JX69 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.