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Protein FAM209A (FAM209A)

Homo sapiens — UniProt Q5JX71

Gene: FAM209AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM209A (FAM209A) is a protein from Homo sapiens identified by UniProt accession Q5JX71, 171 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.

  • UniProt accession: Q5JX71; gene symbol FAM209A.
  • Organism: Homo sapiens.
  • Length: 171 amino acids.
  • Top disease associations (Open Targets): azoospermia, male infertility with teratozoospermia due to single gene mutation and spermatogenic failure 42.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM209A
UniProt accessionQ5JX71
GeneFAM209A
OrganismHomo sapiens
Length171 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (98)

Diseases linked to this target (Open Targets).

  • azoospermia · score 0.11
  • male infertility with teratozoospermia due to single gene mutation · score 0.10
  • spermatogenic failure 42 · score 0.09
  • spermatogenic failure 24 · score 0.08
  • spermatogenic failure 72 · score 0.08
  • spermatogenic failure 51 · score 0.08
  • spermatogenic failure 18 · score 0.08
  • spermatogenic failure 27 · score 0.08
  • spermatogenic failure 46 · score 0.08
  • spermatogenic failure 39 · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5JX71-F1alphafoldPREDICTED58.77—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JX71.

Amino-acid sequence (171 residues)

MWTLKSSLVL LLCLTCSYAF MFSSLRQKTS EPQGKVQYGE HFRIRQNLPE HTQGWLGSKW LWLLFVVVPF VILQCQRDSE KNKEQSPPGL RGGQLHSPLK KKRNASPNKD CAFNTLMELE VELMKFVSKV RNLKRAMATG SGSNLRLRKS EMPADPYHVT ICEIWGEESS S

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM209A?

The strongest Open Targets associations for FAM209A are azoospermia, male infertility with teratozoospermia due to single gene mutation, spermatogenic failure 42, spermatogenic failure 24 and spermatogenic failure 72.

How long is the FAM209A protein?

The Homo sapiens FAM209A protein (UniProt Q5JX71) is 171 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5JX71
GeneFAM209A
OrganismHomo sapiens
Length171
Binders0
Diseases98
View on UniProt