Migration and invasion-inhibitory protein (MIIP)
Homo sapiens — UniProt Q5JXC2
Data last refreshed: (UniProt release unknown)
Key facts
Migration and invasion-inhibitory protein (MIIP) is a protein from Homo sapiens identified by UniProt accession Q5JXC2, 388 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q5JXC2; gene symbol MIIP.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): eosinophil count, sum of eosinophil and basophil counts and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Migration and invasion-inhibitory protein |
|---|---|
| UniProt accession | Q5JXC2 |
| Gene | MIIP |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.33
- sum of eosinophil and basophil counts · score 0.19
- eosinophil percentage of leukocytes · score 0.17
- homocysteine measurement · score 0.11
- neoplasm · score 0.11
- atopic eczema · score 0.09
- seasonal allergic rhinitis · score 0.09
- lymphocyte percentage of leukocytes · score 0.08
- platelet count · score 0.08
- triple-negative breast cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JXC2-F1 | alphafold | PREDICTED | 56.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JXC2.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIIP?
The strongest Open Targets associations for MIIP are eosinophil count, sum of eosinophil and basophil counts, eosinophil percentage of leukocytes, homocysteine measurement and neoplasm.
How long is the MIIP protein?
The Homo sapiens MIIP protein (UniProt Q5JXC2) is 388 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JXC2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JXC2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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